Oil control, barrier repair, pigmentation, anti-aging—one ingredient that genuinely does it all. Plus: the truth about concentration myths.
Niacinamide (nicotinamide) is the active form of Vitamin B3. Unlike many skincare ingredients that do one thing well, niacinamide has documented benefits across multiple skin concerns—making it one of the most well-researched and versatile actives available.
Niacinamide regulates sebum production by reducing the fatty acids and triglycerides in sebum. Studies show 2% niacinamide reduces sebum excretion rate by 23% after 4 weeks. It also helps normalize the lining of pores, making them appear smaller.
2-5% is sufficient for oil control. Higher concentrations don't necessarily mean more sebum reduction.
Ideal for: Oily skin, combination skin, acne-prone skin
Niacinamide is a precursor to NADP+, which is essential for ceramide and fatty acid synthesis in the skin. Studies show it increases ceramide production and strengthens the skin barrier, reducing transepidermal water loss (TEWL).
Niacinamide doesn't stop melanin production—instead, it blocks the transfer of melanin from melanocytes to keratinocytes. This is a different mechanism than tyrosinase inhibitors (like Vitamin C), making them excellent partners.
Reduction in hyperpigmentation with 5% niacinamide over 8 weeks (multiple studies)
Time to see visible improvement in dark spots and uneven tone
Pro tip: Combine with Vitamin C for enhanced brightening—they work via different pathways and don't interfere with each other.
This is one of skincare's biggest misconceptions. Here's what the research actually shows:
Most clinical studies showing benefits used 2-5%. This range delivers results without irritation risk.
Limited evidence of additional benefits. May cause flushing or irritation in some people.
No studies support better results. Higher risk of irritation, flushing, and sensitivity.
After cleansing, before heavier products:
Can be used alongside retinoids:
Old advice said don't mix niacinamide + Vitamin C. This was based on 1960s research using extreme conditions. Modern formulations are safe to use together—and they complement each other beautifully.
Disclaimer: This article is for educational purposes only and is not intended as medical advice. The information presented is based on generally accepted skincare science, but individual results may vary. Always consult a board-certified dermatologist or healthcare provider before making changes to your skincare routine, especially if you have existing skin conditions.
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