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Ingredients: A

Discover advanced actives and age-defying ingredients starting with A — from chemical exfoliants to brightening powerhouses.

Azelaic Acid

The Multitasking Brightener & Acne Fighter

Type

Dicarboxylic Acid

Solubility

Water Soluble

Best For

Acne, Rosacea, Melasma

Found In

Treatment Serums, Creams

Efficacy Level

Clinically Proven

Origin

Grains / Yeast / Synthetic

What It Does

Azelaic acid is a naturally occurring dicarboxylic acid found in grains that offers a rare trifecta: brightening, anti-acne, and anti-inflammatory properties. It inhibits tyrosinase to fade hyperpigmentation, kills acne-causing bacteria, unclogs pores through gentle keratolytic action, and reduces inflammation—making it uniquely effective for acne, rosacea, and melasma. Unlike hydroquinone or retinoids, it's gentle enough for sensitive skin and safe during pregnancy, earning it dermatologist-favorite status.

The Benefits

Treats acne and prevents breakouts

Fades dark spots and melasma

Reduces rosacea redness and bumps

Gentle enough for sensitive skin

Safe during pregnancy

Provides antioxidant benefits

Backed by Science

Clinical trials show 15-20% azelaic acid reduces acne lesions by 50-70% and improves melasma comparably to 4% hydroquinone. Studies in Journal of the American Academy of Dermatology demonstrate its efficacy for rosacea, reducing papules and pustules by 73%. FDA-approved for acne and rosacea, it's one of few ingredients safe and effective for multiple inflammatory skin conditions.

Formulation Insight

Azelaic acid is formulated at 10% (OTC) or 15-20% (prescription) in creams, gels, and foams. Its grainy texture can feel slightly gritty initially but absorbs well. Micronized formulations improve texture. Works across pH 4-7. Pairs well with niacinamide, retinoids, and vitamin C for enhanced brightening. Can be used morning or evening.

Did You Know?

Azelaic acid is one of the few powerful actives considered safe during pregnancy—making it a go-to for expectant mothers dealing with melasma or acne.

How to Use It Safely

  • Typical Concentration: 10% OTC; 15-20% prescription
  • Frequency: Once or twice daily; start slowly if new to actives
  • Pairing: Combines with niacinamide, retinoids, vitamin C
  • Caution: May cause tingling initially; use SPF 30+ daily; safe in pregnancy

Ingredient Source & Sustainability

Azelaic acid is produced through fermentation of grains or yeast, or synthesized chemically. Both methods are sustainable and provide consistent purity. It's vegan, cruelty-free, and biodegradable.

Pairs Well With: